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Are the relationships between mental health issues and being left-behind gendered in China
BACKGROUND: While most existing studies reveal left-behind children (LBC) are prone to suffering from mental health issues, some other literature fails to develop a statistical significance between being left-behind and facing...
p53 and ovarian carcinoma survival
Martin Köbel, Eun-Young Kang, Ashley Weir, Peter F Rambau, Cheng-Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks-Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney-Brooks, Kara L Cushing-Haugen, Cezary Cybulski, Suha Deen, Mona A El-Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, Anna Fischer, Simon A Gayther, Arantzazu Barquin-Garcia, Aleksandra Gentry-Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez-Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz-Ares, Teresa Ramón Y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido Dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton
Apr 17, 2023
p53 ovarian cancer Prognosis Clear cell TP53 High-grade Serous Carcinoma Endometrioid Humans Carcinoma Endometrioid Ovarian Neoplasms Female Tumor Suppressor Protein p53 Carcinoma Ovarian Epithelial
Published by: The journal of pathology. Clinical research
The COSI trial
Camilla Rosan, Kim Alyousefi-van Dijk, Zoe Darwin, Daphne Babalis, Victoria Cornelius, Rachel Phillips, Lani Richards, Hannah Wright, Steve Pilling, Pasco Fearon, Elena Pizzo, Peter Fonagy
Apr 13, 2023
Background
Perinatal mental health difficulties affect up to 27% of birthing parents during pregnancy and the first postnatal year, and if untreated are associated with difficulties in bonding and long-term adverse...
Child Development randomised controlled trial Perinatal mental health Child Attachment Circle Of Security-parenting Parent-infant Bonding Humans Single-Blind Method Parenting Community Mental Health Services Pregnancy Quality of life Child Cost-Benefit Analysis England Female Multicenter Studies as Topic Randomized Controlled Trials as Topic
Published by: Trials
Maternal immunisation against Group B Streptococcus
Simon R Procter, Bronner P Gonçalves, Proma Paul, Jaya Chandna, Farah Seedat, Artemis Koukounari, Raymond Hutubessy, Caroline Trotter, Joy E Lawn, Mark Jit
Apr 14, 2023
Background
Group B Streptococcus (GBS) can cause invasive disease (iGBS) in young infants, typically presenting as sepsis or meningitis, and is also associated with stillbirth and preterm birth. GBS vaccines are under...
Humans Streptococcus Agalactiae Streptococcal Infections premature birth vaccines Immunization Vaccination Bayes Theorem Pregnancy Quality of life Infant Infant Newborn Cost-Benefit Analysis Female Stillbirth
Published by: PLoS Medicine
High prevalence of cardiometabolic risk factors amongst young adults in the United Arab Emirates
Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S Al Dhaheri, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammad Hag Ali, E Murat Tuzcu, Naima Oumeziane, Omar El-Shahawy, Rami H Al-Rifai, Scott Sherman, Syed M Shah, Thekra Alzaabi, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Luai A Ahmed, Raghib Ali
Apr 15, 2023
Background
Cardiovascular disease (CVD) is the leading cause of death in the world. In the United Arab Emirates (UAE), it accounts for 40% of mortality. CVD is caused by multiple cardiometabolic risk factors (CRFs)...
Hypertension obesity cardiovascular disease Dyslipidemia Central obesity Non-communicable disease cardiometabolic risk factors Dysglycemia Humans Cardiovascular Diseases prevalence Risk Factors Adult United Arab Emirates Female Male Dyslipidemias Young Adult obesity Abdominal
Published by: BMC cardiovascular disorders
Primitive haematopoiesis in the human placenta gives rise to macrophages with epigenetically silenced HLA-DR.
Jake R Thomas, Anna Appios, Emily F Calderbank, Nagisa Yoshida, Xiaohui Zhao, Russell S Hamilton, Ashley Moffett, Andrew Sharkey, Elisa Laurenti, Courtney W Hanna, Naomi McGovern
Apr 17, 2023
The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. Although this process is thought to be spatially restricted to the yolk sac in the mouse...
MACROPHAGES Placenta Animals Humans Mice HLA-DR Antigens Hematopoiesis Embryonic Development Pregnancy Female
Published by: Nature Communications
Impact on alcohol selection and online purchasing of changing the proportion of available non-alcoholic versus alcoholic drinks
Natasha Clarke, Anna K M Blackwell, Jennifer Ferrar, Katie De-loyde, Mark A Pilling, Marcus R Munafò, Theresa M Marteau, Gareth J Hollands
Apr 17, 2023
Background
Increasing the availability of non-alcoholic options is a promising population-level intervention to reduce alcohol consumption, currently unassessed in naturalistic settings. This study in an online retail...
Published by: PLoS Medicine
Determinants of QuantiFERON Plus-diagnosed tuberculosis infection in adult Ugandan TB contacts
Jonathan Mayito, Adrian R Martineau, Divya Tiwari, Lydia Nakiyingi, David P Kateete, Stephen T Reece, Irene Andia Biraro
Apr 17, 2023
Background
The tuberculin skin test is commonly used to diagnose latent tuberculosis infection (LTBI) in resource-limited settings, but its specificity is limited by factors including cross-reactivity with BCG vaccine...
Humans Tuberculosis HIV Infections Tuberculin Test Cross-Sectional Studies Adult Uganda Female Male Latent Tuberculosis Interferon-gamma Release Tests
Published by: PLOS ONE
Large scale crowdsourced radiotherapy segmentations across a variety of cancer anatomic sites.
Kareem A Wahid, Diana Lin, Onur Sahin, Michael Cislo, Benjamin E Nelms, Renjie He, Mohammed A Naser, Simon Duke, Michael V Sherer, John P Christodouleas, Abdallah S R Mohamed, James D Murphy, Clifton D Fuller, Erin F Gillespie
Apr 17, 2023
Clinician generated segmentation of tumor and healthy tissue regions of interest (ROIs) on medical images is crucial for radiotherapy. However, interobserver segmentation variability has long been considered a significant...
Humans Neoplasms Tomography X-Ray Computed Radiotherapy Planning Computer-Assisted Radiation Oncology Image Processing Computer-Assisted Female Crowdsourcing
Published by: Scientific data
Spatial multiomics map of trophoblast development in early pregnancy.
Anna Arutyunyan, Kenny Roberts, Kevin Troulé, Frederick C K Wong, Megan A Sheridan, Ilia Kats, Luz Garcia-Alonso, Britta Velten, Regina Hoo, Elias R Ruiz-Morales, Carmen Sancho-Serra, Jarrod Shilts, Louis-Francois Handfield, Luca Marconato, Elizabeth Tuck, Lucy Gardner, Cecilia Icoresi Mazzeo, Qian Li, Iva Kelava, Gavin J Wright, Elena Prigmore, Sarah A Teichmann, Omer Ali Bayraktar, Ashley Moffett, Oliver Stegle, Margherita Y Turco, Roser Vento-Tormo
Apr 17, 2023
The relationship between the human placenta-the extraembryonic organ made by the fetus, and the decidua-the mucosal layer of the uterus, is essential to nurture and protect the fetus during pregnancy. Extravillous trophoblast...
Myometrium Decidua Organoids Stem Cells Trophoblasts Placenta Humans Transcription Factors maternal-fetal relations Cell Communication Cell Differentiation Cell Movement Pregnancy Pregnancy Trimester First Female Single-Cell Analysis Transcriptome multiomics
Published by: Nature